Hyperbaric Oxygen Therapy

Filler-Induced Vascular Occlusion
Filler-induced vascular occlusion is a rare but serious complication that can occur after cosmetic dermal filler injections. It happens when filler material unintentionally enters or compresses a blood vessel, blocking normal blood flow to the surrounding skin and tissues.
When blood flow is reduced or cut off, the affected tissue may not receive enough oxygen. Without prompt treatment, this can lead to skin injury, tissue damage, or, in severe cases, tissue loss.
Common signs and symptoms may include:
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Sudden pain during or after injection
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Blanching or whitening of the skin
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Dusky, gray, or purple discoloration
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Mottling or a net-like pattern on the skin
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Coolness of the affected area
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Delayed capillary refill
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Increasing pain or skin changes over hours to days
Symptoms can appear immediately or may develop gradually after the procedure.
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Studies on Filler-Induced Vascular Occlusion and HBOT
Vascular complications with injection implants: treatment with hyperbaric chamber
Danuza Dias Alvesa , Honorio Sampaio Menezes a , Roberto Chacurb , Rodrigo Cadore Mafaldoa , Nıvea MariaBordin da Silva Chacurb , Leandro Dias Gomes a , Raıssa Nardia ,Gabriella Andressa Marchesin de Castro a , Vanessa Pletsch Brendler Borges c andManuela Guimar~aes Dias Gomes
Abstract
Introduction: The use of facial fillers has increased over the years because they are less invasive and present lower risks and faster results, along with shorter recovery time.Objective: This study aimed to analyze the use of hyperbaric oxygen therapy as a possible treatment for vascular complications resulting from facial fillers.
Methodology: This is a retrospective study of a series of patients treated at with hyperbaric oxygen therapy at the Brazilian Institute for Hyperbaric Oxygen Therapy (Instituto de Oxigenoterapia Hiperbarica do Brasil), after vascular complications from facial fillers.
Conclusion: The association of oxygen therapy in a hyperbaric chamber with the conventional protocol for treating vascular occlusion from facial filler procedures was found to be effective.
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Kelly Johnson-Arbor, MD, MedStar Georgetown University Hospital; 3800 Reservoir Road NW; Washington, DC 20007; USA
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Abstract
Introduction: Arterial vascular occlusion is a rare complication of dermal filler injection. This case report describes the successful use of hyperbaric oxygen therapy in a patient with vascular occlusion after a permanent dermal filler was injected.
Case Report: A 51-year-old woman underwent an injection of non-resorbable polymethylmethacrylate microspheres into her nasolabial folds. Several hours later, she experienced dusky discoloration of the right nasolabial fold and surrounding livedo skin changes, consistent with vascular occlusion. Treatment with warm compresses and topical nitroglycerin was initiated, and the patient was referred for hyperbaric oxygen therapy. The tissue discoloration improved significantly after the administration of six hyperbaric treatments.
Discussion: While hyaluronidase is recognized as a treatment option for vascular occlusion associated with using temporary fillers containing hyaluronic acid, it may also be beneficial for patients who experience vascular occlusion after administration of permanent fillers. Hyperbaric oxygen therapy, which results in hyperoxygenation of ischemic tissue and mitigation of the associated inflammatory response, may also benefit patients who experience vascular occlusion after permanent filler injection.
Conclusions: Administration of hyaluronidase and hyperbaric oxygenation should be considered for patients who develop arterial occlusions after dermal filler placement, regardless of the type of injected filler.
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Adriana Rodriguez-Valera MD1,2 | Francisco Nieto-Lopez PhD1,2
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Abstract
Introduction: Aesthetic medicine is characterized by the efficacy and safety of treatments. Although sometimes adverse events could be occurred, in this case vascular occlusion is the most serious of them. The tissue is deprived of oxygen and there is a possibility of necrosis, so it is necessary to remove the tissue filler and promote oxygenation.
Objective: We propose the hyperbaric oxygenation treatment to oxygenate the tissue after vascular occlusion generated by a tissue filler such as Hyaluronic Acid.
Results: We show how hyperbaric oxygenation treatment is an adjuvant therapy after vascular occlusion, improving tissue regeneration and prevent or limit scars or sequelae.
Conclusion: Hyperbaric oxygenation treatment is a safe and effective method to treat vascular accident, improving tissue oxygenation in early cases and improving tissue regeneration in cases with necrosis.



